abstract：:Renal dysfunction is increasingly recognized as a potential clinical feature of mitochondrial cytopathies such as mitochondrial encephalomyopathy, lacticacidosis and stroke-like episodes (MELAS) syndrome. Five cases of MELAS syndrome with renal involvement from 4 unrelated families are presented in this case series. T...

journal_title：Clinical nephrology

authors： Seidowsky A,Hoffmann M,Glowacki F,Dhaenens CM,Devaux JP,de Sainte Foy CL,Provot F,Gheerbrant JD,Hummel A,Hazzan M,Dracon M,Dieux-Coeslier A,Copin MC,Noël C,Buob D

更新日期：2013-12-01 00:00:00

abstract：BACKGROUND:Idiopathic membranous nephropathy (IMN) is a rare form of childhood nephropathy. To date there are no standardized protocols of management for this condition in children. The aim of this study is to report on 4 children with IMN who were treated with mycophenolate mofetil (MMF). METHODS:MMF was given in com...

journal_title：Clinical nephrology

authors： Bhimma R,Naicker E,Ramdial PK

更新日期：2013-12-01 00:00:00

abstract：:Calciphylaxis, or calcific uremic arteriopathy (CUA), is characterized by metastatic calcification in the media of small arteries and arterioles leading to cutaneous necrosis. It is most commonly seen in patients with end stage renal disease who have elevated serum calcium × phosphorus (Ca × P) product. Normalization ...

journal_title：Clinical nephrology

authors： Sandhu G,Casares P,Ranade A,Jones J,Amar LI,Guisado D,Chan G,Smith SD

更新日期：2013-10-01 00:00:00

abstract：:Intravascular large B-cell lymphoma (IVLBCL) is a rare type of non- Hodgkin lymphoma characterized by a disseminated intravascular proliferation of tumor cells in the lumina of small vessels. Although the kidney is one of the target organs of IVLBCL, lymphoma cells that localize only in glomeruli are extremely rare. W...

journal_title：Clinical nephrology

authors： Zhu J,Chen H,Ding G,Chen C

更新日期：2013-10-01 00:00:00

abstract：:Recently, the use of herbal remedies and complementary and alternative medicine has increased globally. Kudzu root (Pueraria lobata) is a plant commonly used in traditional medicine to promote health. A middle-aged woman consumed kudzu root juice to promote health and well-being for 10 days. Subsequently, she develope...

journal_title：Clinical nephrology

authors： Jung JM,Kwon SH,Noh H,Han DC,Jeon JS,Jin SY

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:This study explores sleep problems in dialysis patients and the associations to health-related quality of life (HRQoL) and depression. A comparison between different validated sleep questionnaires was done in order to find an appropriate diagnostic tool in clinical practice. METHODS:In a cross-sectional stu...

journal_title：Clinical nephrology

authors： Brekke FB,Amro A,Hortemo Østhus TB,Dammen T,Waldum B,Os I

更新日期：2013-08-01 00:00:00

abstract：AIM:To assess the prognostic implications of serum uric acid levels on patients with IgA nephropathy in a longitudinal 8-year follow-up study and to identify an association between serum uric acid levels and the clinical and pathological phenotypes of IgA nephropathy. SUBJECTS AND METHODS:We reviewed the files of all ...

journal_title：Clinical nephrology

authors： Cheng GY,Liu DW,Zhang N,Tang L,Zhao ZZ,Liu ZS

更新日期：2013-07-01 00:00:00

abstract：:We present a 32-year-old woman who developed hyperammonemic encephalopathy during hemodialysis. She was rather well before 2009 when receiving peritoneal dialysis due to chronic interstitial nephritis. Due to a refractory peritonitis, the treatment was shifted to hemodialysis in January 2009. About 1 year later, she w...

journal_title：Clinical nephrology

authors： Yang SF,Tseng HS,Huang HC,Hsin IF,Yao YH,Chen JY

更新日期：2013-06-01 00:00:00

abstract：AIM:To investigate the impact of statin medications on urinary stone formation in hyperlipidemic patients. MATERIAL AND METHODS:We searched outpatient military electronic health records from the Southwestern United States to identify adult patients with hyperlipidemia and urolithiasis. Military facilities serve active...

journal_title：Clinical nephrology

authors： Sur RL,Masterson JH,Palazzi KL,L'Esperance JO,Auge BK,Chang DC,Stoller ML

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The long-term efficacy and safety of cyclosporine (CyA) in the treatment of adult minimal change nephrotic syndrome (MCNS) was examined. METHODS:The medical record of 15 patients diagnosed with MCNS by renal biopsy and treated with CyA for at least 2 years were reviewed. RESULTS:The mean administration per...

journal_title：Clinical nephrology

authors： Inoue M,Yumura W,Morishita Y,Ito C,Hamano Y,Ando Y,Muto S,Kusano E

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Kidney injury molecule-1 (KIM-1), neutrophil gelatinase-associated lipocalin (NGAL) and interleukin 18 (IL-18) are three of the most promising biomarkers for the early detection of acute kidney injury. In the present study, to determine whether a combination of the three biomarkers enhances their predictive ...

journal_title：Clinical nephrology

authors： Luo Q,Zhou F,Dong H,Wu L,Chai L,Lan K,Wu M

更新日期：2013-02-01 00:00:00

abstract：:Studies have documented an association between chronic kidney disease (CKD) and increased risk of end stage renal disease, death and comorbidities, including cardiovascular disease and metabolic syndrome, in the general population. However, there is little data on the relationship between CKD and ADE (AIDS defining ev...

journal_title：Clinical nephrology

authors： Alves TP,Wu P,Ikizler TA,Sterling TR,Stinnette SE,Rebeiro PF,Ghosh S,Hulgan T

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:High-tone external muscle stimulation (HTEMS) has been shown to ameliorate painful peripheral neuropathy of dialysis patients. We hypothesized that HTEMS could also lead to improved parameters of health-related quality of life (HRQOL). METHODS:25 end-stage renal disease (ESRD) patients (17 men/8 women, mean ...

journal_title：Clinical nephrology

authors： Klassen A,Racasan S,Gherman-Caprioara M,Kürner B,Blaser C,Bahner U,Heidland A

更新日期：2013-01-01 00:00:00

abstract：:A 76-year old African-American male presented with profound renal failure within 2 weeks after a screening colonoscopy. Polyethylene glycol (PEG) was the sole oral preparatory agent. The significantly elevated lactate dehydrogenase (LDH) and biopsy findings were consistent with acute renal cortical necrosis (RCN). PEG...

journal_title：Clinical nephrology

authors： Hammadah M,Gaber L,Raghavan R

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) not requiring dialysis have a high prevalence of 25-hydroxyvitamin D (25(OH)D) deficiency but the relationship between 25(OH)D levels and metabolic syndrome is unknown in this population. METHODS:This study analyzed stored plasma samples from 495 non-diabetic subje...

journal_title：Clinical nephrology

authors： Seiki S,Chonchol M,Cheung AK,Kaufman JS,Greene T,Roberts WL,Smits G,Kendrick J,HOST Investigators.

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To determine whether the absence of mesangial IgG deposits is associated with the absence of elevated blood levels of galactose-deficient IgA1 (Gd-IgA1) in pediatric patients with IgA nephropathy (IgAN). DESIGN AND METHODS:Serum Gd-IgA1 levels were determined by ELISA using an N-acetylgalactosamine-specific ...

journal_title：Clinical nephrology

authors： Eison TM,Hastings MC,Moldoveanu Z,Sanders JT,Gaber L,Walker PD,Lau KK,Julian BA,Novak J,Wyatt RJ

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) complicates more than 7% of all in-hospital patients. The aim of this study is to investigate the differences in community, hospital and intensive care unit-acquired AKI in patients undergoing nephrology consultation in a tertiary hospital in a developing country. METHODS:An observ...

journal_title：Clinical nephrology

authors： Daher EF,Silva Junior GB,Santos SQ,R Bezerra CC,Diniz EJ,Lima RS,Babosa CA,C Guimarães AA,Mota RM,Abreu KL,Libório AB

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Antiviral prophylaxis has been shown to prevent hepatic dysfunction in Hepatitis B virus (HBV)-positive kidney transplantation recipients (KTRs). However the long-term effects of antiviral prophylaxis on the patient death, graft loss, or hepatic decompensation have not been determined. METHOD:We therefore r...

journal_title：Clinical nephrology

authors： Park KS,Yang WS,Han DJ,Park JB,Park JS,Park SK

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Lanthanum carbonate (LC) is a non-calcium-containing phosphate binder and shows a comparable effect with other phosphate binders on hyperphosphatemia in dialysis patients. LC also contributes to a reduced oral calcium load compared with calcium carbonate (CaC) treatment. However, no crossover studies which c...

journal_title：Clinical nephrology

authors： Toida T,Fukudome K,Fujimoto S,Yamada K,Sato Y,Chiyotanda S,Kitamura K

更新日期：2012-09-01 00:00:00

abstract：:Transient hyperphosphatasemia (TH) is characterized by the isolated elevation of serum alkaline phosphatase (ALP) in children. There is no evidence of liver or bone disease and the ALP levels return to normal within 4 months. Few adult cases have been reported. Here, we report the case of TH in a 54-year-old woman, wh...

journal_title：Clinical nephrology

authors： Lee HJ,Seo JW,Lee DW,Kim HJ,Park DJ,Chang SH

更新日期：2012-08-01 00:00:00

abstract：:The identification of an effective marker of acutely changing kidney function is a priority in clinical nephrology. While serum creatinine is the most widely used surrogate for glomerular filtration rate (GFR), its vulnerability to non-glomerular clearance results in biased estimates of GFR and may delay the identific...

journal_title：Clinical nephrology

authors： Odutayo A,Cherney D

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Elevated serum phosphorus has been identified as a cardiovascular risk factor. This study aimed to assess the effectiveness of dietary intervention to reduce phosphorus intake and to improve the calcium-phosphorus metabolism in hemodialysis patients. DESIGN:Patients were included in a 6-month, 2-group exper...

journal_title：Clinical nephrology

authors： Lou LM,Caverni A,Gimeno JA,Moreno R,Pérez J,Alvarez R,Campos B,García M,Gutiérrez A,Bielsa S,Castilla J,Sanz A,Martin F,Aragon CKD Research Group.

更新日期：2012-06-01 00:00:00

abstract：:This retrospective data analysis was undertaken to examine the biochemical differences between renal stone formers with normocalcemic hyperparathyroidism (NHPT) and those with normal parathyroid hormone (PTH) levels. Our goal was to ascertain whether 25-hydroxyvitamin D (25(OH)D) status related to PTH levels in this p...

journal_title：Clinical nephrology

authors： Pipili C,Sekecioglu N,Oreopoulos DG

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:Endothelial dysfunction (ED) is a key event in the development of atherosclerotic cardiovascular disease (CVD) in patients with chronic kidney disease (CKD). Association of hyperuricemia with CVD has been previously reported in the nonuremic population. In this prospective study, we aimed to evaluate the eff...

journal_title：Clinical nephrology

authors： Yelken B,Caliskan Y,Gorgulu N,Altun I,Yilmaz A,Yazici H,Oflaz H,Yildiz A

更新日期：2012-04-01 00:00:00

abstract：:Secondary hyperparathyroidism (SHPT) is associated with poor outcome including mortality, hospitalization, as well as greater healthcare resource utilization and costs in chronic kidney disease (CKD). We hypothesized that SHPT is also associated with poor self reported health-related quality of life (HRQOL) in prevale...

journal_title：Clinical nephrology

authors： Malindretos P,Sarafidis P,Lazaridis A,Nikolaidis P

更新日期：2012-03-01 00:00:00

abstract：INTRODUCTION:Arterial stiffness is an important contributor to the increased cardiovascular burden of uremia. The aim of the study was to identify determinants of arterial stiffness progression in peritoneal dialysis (PD) patients with strict volume control. PATIENTS AND METHODS:89 prevalent PD patients were enrolled....

journal_title：Clinical nephrology

authors： Demirci MS,Gungor O,Kircelli F,Carrero JJ,Tatar E,Demirci C,Kayikcioglu M,Asci G,Toz H,Ozkahya M,Ok E

更新日期：2012-02-01 00:00:00

abstract：:Associations between secondary focal segmental glomerulosclerosis and both obesity and obstructive sleep apnea have been previously described. Current theory suggests obesity induces glomerular hyperfiltration, leading to glomerulosclerosis. We describe a case of focal segmental glomerulosclerosis in the setting of se...

journal_title：Clinical nephrology

authors： Hall IE,Kashgarian M,Moeckel GW,Dahl NK

更新日期：2012-01-01 00:00:00

abstract：:The chronic kidney disease (CKD) population has a high incidence of sleep disorders, including sleep apnea (SA) and periodic limb movements in sleep (PLMS). SA and PLMS often occur concurrently and may predict mortality in the end stage renal disease (ESRD) population. In this study, we investigated whether sleep frag...

journal_title：Clinical nephrology

authors： Benz RL,Pressman MR,Wu X

更新日期：2011-12-01 00:00:00

abstract：:We report the case of a 53-year-old woman treated for 8 years with Betaferon® (interferon-β-1b), who developed mild renal failure with hypertension, proteinuria and glomerular hematuria. Kidney biopsy was consistent with thrombotic microangiopathy (TMA). Considering the strong evidence of interferon-α causing TMA and ...

journal_title：Clinical nephrology

authors： Broughton A,Cosyns JP,Jadoul M

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND/AIM:Cinacalcet, an allosteric modulator of the calcium sensing receptor, effectively reduces serum parathyroid hormone (PTH) in patients with secondary hyperparathyroidism. It is not well known whether bone mineral density (BMD) of hemodialysis patients with secondary hyperparathyroidism is altered after cin...

journal_title：Clinical nephrology

authors： Ishimura E,Okuno S,Tsuboniwa N,Ichii M,Yamakawa K,Yamakawa T,Shoji S,Nishizawa Y,Inaba M

更新日期：2011-10-01 00:00:00

abstract：:Dissection of a renal artery is rare and is usually associated with underlying arterial disease. Bilateral renal artery dissection following extreme exertion is exceptionally uncommon, and thus presents a diagnostic challenge. We report a case of a middle-aged, otherwise healthy man who presented to the hospital with ...

journal_title：Clinical nephrology

authors： Baroudi S,Bastani B,Balci N,Bieneman BK,Sobti P,Kudva GC

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Although it is generally felt that a catheter with a locking string can achieve better fixation and thus prevent catheter displacement, no formal study has ever substantiated this. METHODS:We retrospectively reviewed the charts from 80 patients (mean age of 64.6 ± 14.76 y) who underwent percutaneous nephros...

journal_title：Clinical nephrology

authors： Chuang MT,Lu CH,Tsai YS,Tsai HM,Kuo TN,Liu YS

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Uncontrolled hy-per-parathyroidism causes bone marrow fibrosis, leading to erythropoietin (EPO) resistance. Medical treatment with cinacalcet is effective in reducing plasma parathyroid hormone (PTH) levels, but its effect on darbepoetin dosing is unknown. METHODS AND AIMS:We conducted a retrospective cohor...

journal_title：Clinical nephrology

authors： Battistella M,Richardson RM,Bargman JM,Chan CT

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:Frequent dosing and requirements for dose adjustments of erythropoiesis-stimulating agents (ESAs) create significant burdens for healthcare providers and have been associated with hemoglobin (Hb) cycling, hampering maintenance of target Hb levels. We compared the frequency of dose changes in dialysis patient...

journal_title：Clinical nephrology

authors： Mann JF,de Francisco A,Nassar G,Canaud B

更新日期：2011-07-01 00:00:00

abstract：:Renal hypouricemia is a clinical disorder attributed to an increased renal urate excretion rate and is well known to involve a high risk of urolithiasis and exercise-induced acute kidney injury (AKI). This report concerns two interesting cases of nephrotic syndrome (NS)-induced AKI associated with renal hypouricemia. ...

journal_title：Clinical nephrology

authors： Takeda Y,Abe A,Nakanishi S,Umezu M,Hirano K,Hayakawa H,Ohno I,Ichida K,Yamaguchi Y,Hosoya T,Fukagawa M

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND/AIMS:Calciphylaxis is a rare condition with dismal prognosis that affects patients with ESRD. Sodium thiosulfate (STS) may play a therapeutic role but its proposed efficacy is based on case reports and thus subject to publication bias. METHODS:We identified all patients who received STS for any indication o...

journal_title：Clinical nephrology

authors： Noureddine L,Landis M,Patel N,Moe SM

更新日期：2011-06-01 00:00:00

abstract：AIMS:Nephropathia epidemica (NE) is mild type of hemorrhagic fever caused by Puumala (PUU) hantavirus. Renal biopsy typically shows acute tubulointerstitial nephritis and complete recovery is the usual outcome. We previously described 5 patients with membranoproliferative glomerulonephritis (MPGN) after acute NE. We no...

journal_title：Clinical nephrology

authors： Miettinen M,Mäkelä S,Haapala M,Helanterä A,Helin H,Vänttinen T,Mustonen J

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Abnormal mineral metabolism is associated with increased morbidity and mortality in dialysis patients. Therefore, the goal of this study was to compare a) mineral metabolism control among a cohort of Canadian peritoneal dialysis (PD) patients to K/DOQI-defined targets and b) the effect of different treatment...

journal_title：Clinical nephrology

authors： Soroka SD,Beard KM,Mendelssohn DC,Cournoyer SH,Da Roza GA,Geary DF

更新日期：2011-05-01 00:00:00

abstract：:The use of C4d staining as a tissue marker for humoral immunity has served an important role in allowing pathologists to more accurately diagnose acute antibody-mediated rejection (AMR) in renal and other allograft biopsies, and also to recognize the contribution of humoral immunity to lesions of chronic renal allogra...

journal_title：Clinical nephrology

authors： Haas M

更新日期：2011-04-01 00:00:00

abstract：AIM:The correlation between kidney function and coronary artery disease (CAD) severity as assessed by an angiographic score has not yet been studied in the South Asian population. We sought to estimate the association by performing a single-center, cross-sectional study. PATIENTS AND METHODS:The estimated glomerular f...

journal_title：Clinical nephrology

authors： Javed F,Nadkarni GN,Khan SA,Sabharwal MS,Annapureddy N,Benjo A,Aziz EF,Herzog E

更新日期：2011-04-01 00:00:00